Buddha is Tezuka's imagined life of Gautama Buddha. First published in 1972, it finally finished a decade later in December of '83. It remains one of Tezuka's most acclaimed series of his career and one of his last epic manga series.
There are plenty of breaks in the drama for humor and even a cameo by Astro boy scientist Professor Ochanomizu. I am hoping that Tezuka puts himself into this series for a cameo. He does that from time to time and it's so cute.